Aftercare After Injectable Treatments: The First 24 Hours, the First Week and Beyond

Good aftercare is mostly about leaving the treated area alone for a day, knowing what is normal, and recognising the few signs that need urgent attention. Here is Helena's practical guide for anti-wrinkle injections, dermal fillers, skin boosters and polynucleotides.

5 min read · 8 September 2026

In this article

The short answer

Good aftercare is mostly about leaving the treated area alone for a day, staying alert to a few warning signs, and giving each treatment the time it needs. Anti-wrinkle injections show their full effect at around two weeks. Dermal fillers settle over one to two weeks. Skin boosters and polynucleotides work gradually, and Helena asks for at least three months before judging a skin-regeneration course. Results vary between individuals.

The first 24 hours

The first day is when the treated area is most vulnerable. A few simple habits make a difference.

  • Keep the area clean. Avoid touching, rubbing or massaging unless Helena has shown you how. Wait until the next day before applying make-up over injection points.
  • Stay upright. After anti-wrinkle injections, avoid lying flat or bending forward for about four hours, and skip hats or headbands that press on the forehead.
  • Skip heat and exertion. No hard exercise, saunas, steam rooms, hot yoga or sunbeds for 24 hours. Heat widens blood vessels and can increase swelling and bruising.
  • Avoid alcohol. It thins the blood slightly and can make bruising worse.
  • Hold off on other treatments. No facials, massage, microneedling or laser over the treated area until Helena says it is fine.

The first week

Swelling from dermal fillers usually peaks within the first two days and then settles. Lips tend to swell the most and can look uneven for several days, which is normal. Sleep with your head slightly raised for the first couple of nights if you can.

Small bruises can appear a day or two after treatment and fade over a week or so. Arnica cream or a cool compress, applied gently, can help. Avoid aspirin or ibuprofen for pain unless you take them for a medical reason; paracetamol is a better choice.

Keep sun exposure low and use a broad-spectrum SPF. Skin boosters, polynucleotides and other skin treatments leave tiny injection marks that fade over a few days, and the skin can feel slightly bumpy before the product disperses.

Where possible, delay dental work for two weeks after lip or lower-face filler. Dental procedures can introduce bacteria into the bloodstream while the filler is settling.

When to expect results

Timing differs by treatment, and knowing what to expect stops unnecessary worry.

  • Anti-wrinkle injections: movement begins to soften after three to five days, with the full effect at around two weeks. Helena reviews at two weeks and can adjust if needed.
  • Dermal fillers: you see the shape immediately, but the true result appears once swelling has gone, usually within two weeks.
  • Skin boosters and polynucleotides: these work by improving skin quality from within, so change is gradual. Helena asks for at least three months in skin-regeneration courses before judging the result, and most protocols involve a course of sessions spaced weeks apart.

Helena’s clients tend to describe feeling refreshed rather than changed, and she is clear that results depend on following the aftercare and completing the course.

What is normal, and what needs urgent attention

Some reactions are expected and settle on their own:

  • Mild swelling, redness or tenderness at injection points
  • Small bumps that flatten within hours after anti-wrinkle injections, or within a few days after skin boosters
  • One or two small bruises
  • A mild headache in the first day or two after forehead injections
  • Slight lumpiness under the skin after filler that softens as the product integrates

If anything lasts longer than you expected, or you are simply unsure, get in touch.

Some signs need prompt attention, particularly after dermal filler. Contact Helena immediately if you notice any of the following, and seek urgent medical help if you cannot reach her:

  • Increasing pain rather than pain that is easing, especially if it feels out of proportion to the treatment
  • Skin that turns white, blotchy, dusky or purplish in or near the treated area, or a net-like pattern spreading across the skin
  • Any change to your vision, however small
  • Signs of infection such as spreading redness, heat, pus or fever
  • Severe or worsening swelling, or any difficulty swallowing or breathing

Colour change and increasing pain can mean filler is affecting the blood supply to the skin. It is uncommon but time-sensitive. Helena gives you her direct contact details at your appointment; keep them to hand for the first few days.

Your two-week review

Helena books a review at two weeks after anti-wrinkle injections and dermal filler. By then swelling has settled and anti-wrinkle injections have taken full effect, so it is the right moment to check symmetry, see how you feel and make small adjustments where appropriate. For skin-regeneration courses, the review is a chance to plan the next session and see how your skin is responding.

If you are yet to have treatment, the guide to your first consultation explains how the plan is built, and safety and standards covers how the clinic prepares for the rare complication.

In short: rest the area for a day, avoid heat and alcohol, and give each treatment its own timeline. Small bruises and mild swelling are part of the process. Increasing pain, colour changes to the skin or any vision change are not, and need urgent attention. When in doubt, ask.

Frequently asked questions

What should I avoid after anti-wrinkle injections?

For the first 24 hours avoid rubbing or massaging the area, lying flat or bending forward for around four hours, hard exercise, heat such as saunas, and alcohol. Leave make-up off the injection points until the next day. Gentle facial movement is fine. The full effect appears at around two weeks.

How long does swelling last after dermal filler?

Swelling usually peaks within the first two days and settles over one to two weeks, with lips taking the longest. Small bruises can take a week or so to fade. A cool compress and sleeping slightly raised can help. If swelling worsens rather than improves, contact the clinic.

When should I call the clinic after filler?

Call straight away if you notice increasing pain, skin turning white, dusky or blotchy near the treated area, any change to your vision, or signs of infection such as spreading redness or fever. These are uncommon but time-sensitive. If you cannot reach Helena, seek urgent medical help.

When will I see results from skin boosters or polynucleotides?

Gradually. These treatments improve skin quality from within, so Helena asks for at least three months in skin-regeneration courses before judging the result. Most protocols involve a course of sessions spaced weeks apart. Anti-wrinkle injections, by contrast, show their full effect at around two weeks. Results vary between individuals.