Skin Quality

Mesotherapy

Mesotherapy in Marylebone, London: a bespoke cocktail of vitamins, amino acids and hyaluronic acid delivered into the skin by micro-injection or microneedling over a course of four to six sessions.

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The short answer

What is mesotherapy?

Mesotherapy delivers a blend of nutrients directly into the middle layer of the skin, where a cream cannot reach. The cocktail is usually built around non-cross-linked hyaluronic acid with vitamins, amino acids, minerals and antioxidants, chosen for the concern in front of Helena: dryness, dullness, fine lines or skin that has lost its firmness. It can be placed with a series of very fine micro-injections or spread across the face with microneedling. Mesotherapy does not add volume or change your features. A course of four to six sessions, two weeks apart, is standard. Results vary between individuals.

Areas treated

Why choose mesotherapy at Novaderma Aesthetics

Nutrients placed in the dermis itself, rather than left on the surface
A cocktail curated for your skin at consultation, not a fixed recipe
Choice of micro-injection or microneedling depending on the area and your comfort
No added volume or change of shape, so you still look like yourself
Carried out by a Registered Nurse after a face-to-face consultation
Sequences naturally with skin boosters, polynucleotides and chemical peels in a bespoke plan

Boundaries of practice

What's not treated

Good practice means saying no when indicated:

Pregnancy or breastfeeding
Active acne, cold sores, eczema or any skin infection in the treatment area
Known allergy to any ingredient in the cocktail or to lidocaine where a numbing agent is used
Autoimmune conditions or poor wound healing, assessed individually
Bleeding disorders or blood-thinning medication without agreement from the prescribing clinician
Under 18 years of age

Patient journey

What to expect from a mesotherapy course

Consultation & preparation

Avoid alcohol, aspirin, ibuprofen and fish oil supplements for 24 to 48 hours before treatment to reduce bruising, unless prescribed. Stop retinoids and exfoliating acids for three days beforehand and arrive with clean, makeup-free skin. Tell Helena about any medicines, supplements or previous treatments at your consultation.

During treatment

What is mesotherapy and how does it work?

The skin has an outer barrier that keeps most of what you apply to it on the surface. Mesotherapy bypasses that barrier by placing a nutrient cocktail in the dermis, the layer where collagen, elastin and your own hyaluronic acid live. Hyaluronic acid in the blend draws water into the skin, while vitamins, amino acids and antioxidants give the cells the raw materials they use for repair. The effect is a better hydrated, brighter and more even surface that develops over the course.

What happens at my appointment?

New clients begin with a consultation of up to an hour to go through your concerns and medical history and choose the right blend and delivery method. At each treatment appointment Helena cleanses the skin and applies numbing cream for around 20 minutes. With micro-injections, she places small amounts of the cocktail at close intervals across the area. With microneedling, she passes a sterile, single-use device over the face while the cocktail is worked in. Either way the session takes around 30 to 45 minutes.

How many sessions, and when will I see the result?

Most people have four to six sessions, two weeks apart. Hydration and glow tend to improve early in the course, while texture and firmness take longer as the skin responds. Helena asks you to allow at least three months for skin regeneration before judging the result. Once the course is complete, she will discuss maintenance based on how your skin has responded and how it sits alongside the other treatments in your plan.

Where can I have mesotherapy near me in Marylebone?

Helena treats at UNTIL Marylebone, 1 Orchard Street, London W1H 6HJ, on the corner of Wigmore Street next to Selfridges and three minutes from Bond Street tube. Appointments run Thursday evenings, Fridays and Saturdays, with a second clinic at UNTIL Canary Wharf by appointment. Treatment takes place in a calm, comfortable environment and Helena remains contactable afterwards if you have questions.

Aftercare

Leave the skin free of makeup for 12 to 24 hours and avoid touching or rubbing it. Skip saunas, steam, intense exercise and alcohol for 24 hours, and stay out of direct sun for 48 hours. Redness, small bumps or the odd bruise usually settle within one to three days.

Pricing

Mesotherapy prices in Marylebone

Initial consultation (up to 1 hour) Concerns, medical history and a plan of which treatments belong in your journey

£50

Mesotherapy, per session Micro-injection or microneedling; course of 4 to 6 sessions, 2 weeks apart

From £300

Written and medically reviewed by Helena Casales-Arregui, Advanced Aesthetic Nurse: RN, NMC Registered · DermNet NZ (dermatology reference).

FAQ

Mesotherapy FAQs

What is in a mesotherapy cocktail?

A typical blend combines non-cross-linked hyaluronic acid with vitamins, amino acids, minerals and antioxidants chosen for your skin. Helena selects the mix at your consultation based on whether your main concern is dryness, dullness, fine lines or loss of firmness. She will always tell you exactly what is being used.

Micro-injection or microneedling: which is better?

Both deliver the same ingredients into the skin, just by a different route. Micro-injections place small amounts precisely, which suits targeted areas such as around the eyes or mouth. Microneedling spreads the cocktail evenly across a larger area like the whole face. Helena recommends the method that fits your skin and comfort level.

How many mesotherapy sessions will I need?

Most people have four to six sessions, two weeks apart. Hydration and glow tend to improve early in the course, while texture and firmness take longer as the skin responds. Helena asks you to allow at least three months before judging the result, then discuss maintenance based on how your skin has responded.

Does mesotherapy hurt?

Discomfort is usually mild. Numbing cream is applied beforehand, and the needles used are very fine and shallow. Most people describe a light prickling or scratching sensation rather than pain. The face is a little more sensitive around the eyes and mouth, and Helena works slowly in those areas to keep you comfortable.

How is mesotherapy different from skin boosters?

Skin boosters use a soft hyaluronic acid gel that holds water in the skin for months. Mesotherapy uses a lighter, non-cross-linked hyaluronic acid blended with vitamins and amino acids, delivered in a series of closer sessions. Mesotherapy feeds the skin over a short course; skin boosters hold hydration for longer. Helena sequences both across a year.

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Novaderma Aesthetics • 1 Orchard Street, UNTIL Marylebone, London W1H 6HJ

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Appointments typically available within 1–2 weeks